GPR31 Polyclonal Antibody, Unconjugated, Rabbit

Product Overview

• Article Name: GPR31 Polyclonal Antibody, Unconjugated, Rabbit
• Biozol Catalog Number: BSS-BS-13530R
• Supplier Catalog Number: bs-13530R
• Alternative Catalog Number: BSS-BS-13530R-100
• Manufacturer: Bioss
• Host: Rabbit
• Category: Antikörper
• Application: ELISA, IF, IHC-Fr, IHC-P, WB
• Species Reactivity: Human
• Conjugation: Unconjugated
• Alternative Names: HETER, HETER1, 12-HETER, 12-(S)-hydroxy-5,8,10,14-eicosatetraenoic acid receptor, 12-(S)-HETE receptor, G-protein coupled receptor 31, GPR31

Product Description

High-affinity receptor for 12-(S)-hydroxy-5,8,10,14-eicosatetraenoic acid (12-S-HETE). 12-(S)-HETE is an arachidonic acid metabolite secreted by platelets and tumor cells, and known to induce endothelial cells retraction allowing invasive cell access to the subendothelial matrix, which is a critical step for extravasation or metastasis. Ligand-binding lead to activation of ERK1/2 (MAPK3/MAPK1), MEK, and NF-kappa-B.

Product Properties

• Clonality: Polyclonal
• Concentration: 1ug/ul
• NCBI: 2853
• UniProt: O00270
• Buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
• Source: KLH conjugated synthetic peptide derived from human G protein coupled receptor 31
• Target: GPR31

Application Notes

• Application Dilute: WB(1:300-5000), ELISA(1:500-1000), IHC-P(1:200-400), IHC-F(1:100-500), IF(IHC-P)(1:50-200), IF(IHC-F)(1:50-200), IF(ICC)(1:50-200)