ZAK Polyclonal Antibody, Biotin Conjugated, Rabbit

Product Overview

• Article Name: ZAK Polyclonal Antibody, Biotin Conjugated, Rabbit
• Biozol Catalog Number: BSS-BS-13546R-BIOTIN
• Supplier Catalog Number: bs-13546R-Biotin
• Alternative Catalog Number: BSS-BS-13546R-BIOTIN-100
• Manufacturer: Bioss
• Host: Rabbit
• Category: Antikörper
• Application: ELISA, IHC-Fr, IHC-P
• Species Reactivity: Mouse, Rat
• Conjugation: Biotin
• Alternative Names: AZK, Cervical cancer suppressor gene 4 protein, HCCS 4, HCCS-4, HCCS4, Human cervical cancer suppressor gene 4 protein, Leucine zipper and sterile alpha mot containing kinase, Leucine zipper- and sterile alpha mot-containing kinase, Mitogen activated protein kinase kinase kinase MLT, Mitogen-activated protein kinase kinase kinase MLT, Mixed lineage kinase 7, Mixed lineage kinase related kinase, Mixed lineage kinase related kinase MRK beta, Mixed lineage kinase with a leucine zipper and a sterile alpha mot, Mixed lineage kinase-related kinase, MLK 7, MLK like mitogen activated protein triple kinase, MLK related kinase, MLK-like mitogen-activated protein triple kinase, MLK-related kinase, MLK7, Mlklak, MLT, MLTK, MLTK_HUMAN, MRK, Sterile alpha mot and leucine zipper containing kinase AZK, Sterile alpha mot- and leucine zipper-containing kinase AZK, ZAK.

Product Description

Stress-activated component of a protein kinase signal transduction cascade. Regulates the JNK and p38 pathways. Pro-apoptotic. Role in regulation of S and G2 cell cycle checkpoint by direct phosphorylation of CHEK2. Isoform 1, but not isoform 2, causes cell shrinkage and disruption of actin stress fibers. Isoform 1 may have role in neoplastic cell transformation and cancer development. Isoform 1, but not isoform 2, phosphorylates histone H3 at Ser-28.

Product Properties

• Clonality: Polyclonal
• Concentration: 1ug/ul
• NCBI: 51776
• Buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
• Source: KLH conjugated synthetic peptide derived from human ZAK/HCCS4
• Target: ZAK

Application Notes

• Application Dilute: ELISA(1:500-1000), IHC-P(1:200-400), IHC-F(1:100-500)