Jun D Polyclonal Antibody, Biotin Conjugated, Rabbit
Biozol Catalog Number:
BSS-BS-1393R-BIOTIN
Supplier Catalog Number:
bs-1393R-Biotin
Alternative Catalog Number:
BSS-BS-1393R-BIOTIN-100
Manufacturer:
Bioss
Host:
Rabbit
Category:
Antikörper
Application:
ELISA, IHC-Fr, IHC-P, WB
Species Reactivity:
Rat
Conjugation:
Biotin
Alternative Names:
jun D proto-oncogene, JUND1, AP-1, JUND, JUND1, MGC6245, MGC72300.
The cJun proto-oncogene was first identified as the cellular homolog of the avian sarcoma virus vjun oncogene. JunB and JunD have been shown to be almost identical to cJun in their C terminal regions, which are involved in dimerization and DNA binding, whereas their N terminal domains, which are involved in transcriptional activation, diverge. JunB is a transcription factor involved in regulating gene activity following the primary growth factor response. It binds to the DNA sequence 5-TGA[CG]TCA-3.The protein encoded by this intronless gene is a member of the JUN family, and a functional component of the AP1 transcription factor complex. It has been proposed to protect cells from p53-dependent senescence and apoptosis. Alternate translation initiation site usage, including non-AUG codons, results in the production of different isoforms.
