DDX36, DEAH box protein 36, Dhx36, DHX36_HUMAN, EC 3.6.1.-, KIAA1488, MLE like protein 1, MLE-like protein 1, MLEL1, Probable ATP dependent RNA helicase DHX36, Probable ATP-dependent RNA helicase DHX36, RHAU, RNA helicase associated with AU rich element ARE, RNA helicase associated with AU-rich element ARE.
This gene is a member of the DEAH-box family of RNA-dependent NTPases which are named after the conserved amino acid sequence Asp-Glu-Ala-His in motif II. The protein encoded by this gene has been shown to enhance the deadenylation and decay of mRNAs with 3-UTR AU-rich elements (ARE-mRNA). The protein has also been shown to resolve into single strands the highly stable tetramolecular DNA configuration (G4) that can form spontaneously in guanine-rich regions of DNA. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
