phospho-Dnmt3a (Ser390 + Ser393) Polyclonal Antibody, Biotin Conjugated, Rabbit

Product Overview

• Article Name: phospho-Dnmt3a (Ser390 + Ser393) Polyclonal Antibody, Biotin Conjugated, Rabbit
• Biozol Catalog Number: BSS-BS-14399R-BIOTIN
• Supplier Catalog Number: bs-14399R-Biotin
• Alternative Catalog Number: BSS-BS-14399R-BIOTIN-100
• Manufacturer: Bioss
• Host: Rabbit
• Category: Antikörper
• Application: IHC-Fr, IHC-P, WB
• Species Reactivity: Human
• Conjugation: Biotin
• Alternative Names: Dnmt3a (phospho S390 + S393), Dnmt3a (phospho Ser390 + Ser393), p-Dnmt3a (phospho S390 + S393), DNA (cytosine 5) methyltransferase 3 alpha, DNA (cytosine 5) methyltransferase 3A, DNA (cytosine-5)-methyltransferase 3A, DNA cytosine methyltransferase 3A2, DNA methyltransferase 3a, DNA methyltransferase HsaIIIA, DNA MTase HsaIIIA, DNM3A_HUMAN, DNMT 3a, DNMT, Dnmt3a, DNMT3A2, M.HsaIIIA, MCMT, OTTHUMP00000201149.

Product Description

Required for genome wide de novo methylation and is essential for the establishment of DNA methylation patterns during development. DNA methylation is coordinated with methylation of histones. It modifies DNA in a non-processive manner and also methylates non-CpG sites. May preferentially methylate DNA linker between 2 nucleosomal cores and is inhibited by histone H1. Plays a role in paternal and maternal imprinting. Required for methylation of most imprinted loci in germ cells. Acts as a transcriptional corepressor for ZNF238. Can actively repress transcription through the recruitment of HDAC activity.

Product Properties

• Clonality: Polyclonal
• Concentration: 1ug/ul
• NCBI: 1788
• UniProt: Q9Y6K1
• Buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
• Source: KLH conjugated Synthesised phosphopeptide derived from human Dnmt3a around the phosphorylation site of Ser390 + Ser393
• Target: phospho-Dnmt3a (Ser390 + Ser393)

Application Notes

• Application Dilute: WB(WB=1:500-2000), IHC-P(IHC-P=1:100-500), IHC-F(IHC-F=1:100-500)