IL12A Polyclonal Antibody, AbBy Fluor-647 Conjugated, BF647, Rabbit
Catalog Number:
BSS-BS-14637R-BF647
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| Article Name: | IL12A Polyclonal Antibody, AbBy Fluor-647 Conjugated, BF647, Rabbit |
| Biozol Catalog Number: | BSS-BS-14637R-BF647 |
| Supplier Catalog Number: | bs-14637R-BF647 |
| Alternative Catalog Number: | BSS-BS-14637R-BF647-100 |
| Manufacturer: | Bioss |
| Host: | Rabbit |
| Category: | Antikörper |
| Application: | IF, WB |
| Species Reactivity: | Rat |
| Conjugation: | BF647 |
| Alternative Names: | IL12, IL-12, CLMF p35, CLMF1, CTL maturation factor (TcMF), Cytotoxic lymphocyte maturation factor 1, Cytotoxic lymphocyte maturation factor 35 kDa subunit, IL 12 subunit p35, IL12A, Interleukin 12 alpha chain, Interleukin 12 p35, Interleukin 12A, Natural killer cell stimulatory factor 1, CLMF, CLMF p35, Cytotoxic lymphocyte maturation factor 35 kDa subunit, IL-12 subunit p35, IL-12A, IL12 subunit p35, IL12A, IL12A_HUMAN, Interleukin 12 p35, Interleukin 12A, Interleukin-12 subunit alpha, NFSK, NK cell stimulatory factor chain 1, NKSF1. NK cell stimulatory factor chain 1, NKSF1, p35, IL12A_RAT. |
| IL-12 protein is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract. |
| Application Dilute: | WB(1:300-5000), IF(IHC-P)(1:50-200), IF(IHC-F)(1:50-200), IF(ICC)(1:50-200) |
