C14orf58, Calcium chelate transporter, CCT, FLVC2_HUMAN, CHROMOSOME 14 OPEN READING FRAME 58, EPV, Feline leukemia virus subgroup C cellular receptor family, member 2, FLVCR LIKE ON CHROMOSOME 14q, FLVCRL14q, MFSD7C, PVHH.
This gene encodes a member of the major facilitator superfamily. The encoded transmembrane protein is a calcium transporter. Unlike the related protein feline leukemia virus subgroup C receptor 1, the protein encoded by this locus does not bind to feline leukemia virus subgroup C envelope protein. The encoded protein may play a role in development of brain vascular endothelial cells, as mutations at this locus have been associated with proliferative vasculopathy and hydranencephaly-hydrocephaly syndrome. Alternatively spliced transcript variants have been described. [provided by RefSeq, Aug 2010]
