CAG repeat protein 26, CAGH26, DKFZp666E117, EDIE, EMSY interactor protein, FLJ22043, Glycine tryptophan protein of 182 kDa, Glycine-tryptophan protein of 182 kDa, GW1, GW182, GW182 autoantigen, Hypothetical protein DKFZp566M143, KIAA1460, MGC75384, OTTHUMP00000122485, OTTHUMP00000195164, OTTHUMP00000195165, Protein GW1, TNR6A_HUMAN, TNRC 6A, TNRC6, TNRC6A, Trinucleotide repeat containing 6, Trinucleotide repeat containing 6A, Trinucleotide repeat containing gene 6A protein, Trinucleotide repeat-containing gene 6A protein.
This gene encodes a member of the trinucleotide repeat containing 6 protein family. The protein functions in post-transcriptional gene silencing through the RNA interference (RNAi) and microRNA pathways. The protein associates with messenger RNAs and Argonaute proteins in cytoplasmic bodies known as GW-bodies or P-bodies. Inhibiting expression of this gene delocalizes other GW-body proteins and impairs RNAi and microRNA-induced gene silencing. [provided by RefSeq, Jul 2008]
