phospho-FAK (Tyr577) Polyclonal Antibody, PE Conjugated, Rabbit
Biozol Catalog Number:
BSS-BS-1639R-PE
Supplier Catalog Number:
bs-1639R-PE
Alternative Catalog Number:
BSS-BS-1639R-PE-100
Manufacturer:
Bioss
Host:
Rabbit
Category:
Antikörper
Application:
FC, IF, WB
Species Reactivity:
Mouse
Conjugation:
PE
Alternative Names:
FAK phospho Y577, p-FAK phospho Y577, FADK 1, FADK, FAK 1, FAK related non kinase polypeptide, FAK1, Focal adhesion kinase 1, FRNK, pp125FAK, Protein tyrosine kinase 2, Protein Tyrosine Kinase Cytoplasmic, PTK 2, FAK1_HUMAN, Focal adhesion kinase-related nonkinase, Protein phosphatase 1 regulatory subunit 71, PPP1R71, Protein-tyrosine kinase 2, p125FAK.
Non-receptor protein-tyrosine kinase implicated in signaling pathways involved in cell motility, proliferation and apoptosis. Activated by tyrosine-phosphorylation in response to either integrin clustering induced by cell adhesion or antibody cross-linking, or via G-protein coupled receptor (GPCR) occupancy by ligands such as bombesin or lysophosphatidic acid, or via LDL receptor occupancy. Plays a potential role in oncogenic transformations resulting in increased kinase activity. [SUBCELLULAR LOCATION] Cell junction, focal adhesion. Cell membrane, Peripheral membrane protein, Cytoplasmic side. Note=Constituent of focal adhesions.
