phospho-GRK2 (Ser670) Polyclonal Antibody, Cy3 Conjugated, Rabbit

Product Overview

• Article Name: phospho-GRK2 (Ser670) Polyclonal Antibody, Cy3 Conjugated, Rabbit
• Biozol Catalog Number: BSS-BS-16682R-CY3
• Supplier Catalog Number: bs-16682R-Cy3
• Alternative Catalog Number: BSS-BS-16682R-CY3-100
• Manufacturer: Bioss
• Host: Rabbit
• Category: Antikörper
• Application: IF
• Species Reactivity: Human, Mouse
• Conjugation: Cy3
• Alternative Names: GRK2 (phospho S670), p-GRK2 (phospho S670), G-protein coupled receptor kinase 2, ADRBK 1, ADRBK1, Adrenergic beta receptor kinase 1, BARK 1, BARK, BARK1, Beta adrenergic receptor kinase 1, Beta ARK 1, Beta ARK1, G Protein Coupled Receptor Kinase 2, G protein dependent receptor kinase 2, FLJ16718, GRK 2, ARBK1_HUMAN.

Product Description

The product of this gene phosphorylates the beta-2-adrenergic receptor and appears to mediate agonist-specific desensitization observed at high agonist concentrations. This protein is an ubiquitous cytosolic enzyme that specifically phosphorylates the activated form of the beta-adrenergic and related G-protein-coupled receptors. Abnormal coupling of beta-adrenergic receptor to G protein is involved in the pathogenesis of the failing heart. [provided by RefSeq].

Product Properties

• Clonality: Polyclonal
• Concentration: 1ug/ul
• NCBI: 156
• UniProt: P25098
• Buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
• Source: KLH conjugated synthesised phosphopeptide derived from human GRK2 around the phosphorylation site of Ser670
• Target: phospho-GRK2 (Ser670)

Application Notes

• Application Dilute: IF(IHC-P)(1:50-200), IF(IHC-F)(1:50-200), IF(ICC)(1:50-200)