phospho-IRE1 (Ser724) Polyclonal Antibody, AbBy Fluor-647 Conjugated, BF647, Rabbit

Product Overview

• Article Name: phospho-IRE1 (Ser724) Polyclonal Antibody, AbBy Fluor-647 Conjugated, BF647, Rabbit
• Biozol Catalog Number: BSS-BS-16698R-BF647
• Supplier Catalog Number: bs-16698R-BF647
• Alternative Catalog Number: BSS-BS-16698R-BF647-100
• Manufacturer: Bioss
• Host: Rabbit
• Category: Antikörper
• Application: WB
• Species Reactivity: Human, Mouse, Rat
• Conjugation: BF647
• Alternative Names: IRE1 (phospho S724), p-IRE1 (phospho S724), Endoplasmic reticulum (ER) to nucleus signalling 1, Endoplasmic reticulum to nucleus signaling 1, Endoplasmic reticulum-to-nucleus signaling 1, Endoribonuclease, ER to nucleus signaling 1, ER to nucleus signalling 1, ERN 1, ERN1, ERN1_HUMAN, hIRE 1p, hIRE1p, Inositol requiring 1, Inositol requiring 1, S. cerevisiae, homolog of, Inositol requiring enzyme 1, S. cerevisiae, homolog of, Inositol requiring protein 1, inositol-requiring enzyme 1, Inositol-requiring protein 1, IRE 1, IRE 1a, IRE 1P, Ire1 alpha, Ire1-alpha, IRE1a, Ire1alpha, IRE1P, MGC163277, MGC163279, Protein kinase/endoribonuclease, RGD1559716, Serine/threonine protein kinase/endoribonuclease IRE1.

Product Description

Senses unfolded proteins in the lumen of the endoplasmic reticulum via its N-terminal domain which leads to enzyme auto-activation. The active endoribonuclease domain splices XBP1 mRNA to generate a new C-terminus, converting it into a potent unfolded-protein response transcriptional activator and triggering growth arrest and apoptosis.

Product Properties

• Clonality: Polyclonal
• Concentration: 1ug/ul
• NCBI: 10595
• UniProt: O75460
• Buffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
• Source: KLH conjugated synthesised phosphopeptide derived from human IRE1 around the phosphorylation site of Ser724
• Purity: Purified by Protein A.
• Target: phospho-IRE1 (Ser724)

Application Notes

• Application Dilute: WB(1:300-5000)