Methionine synthase, MTR, 5-methyltetrahydrofolate--homocysteine, methyltransferase, Vitamin-B12 dependent methionine synthase, MS
MTR encodes the enzyme 5-methyltetrahydrofolate-homocysteine methyltransferase. This enzyme, also known as cobalamin-dependent methionine synthase, catalyzes the final step in methionine biosynthesis. Mutations in MTR have been identified as the underlying cause of methylcobalamin deficiency complementation group G.