LXR beta Polyclonal Antibody, PE-Cy7 Conjugated, PE/Cy7, Rabbit

Product Overview

• Article Name: LXR beta Polyclonal Antibody, PE-Cy7 Conjugated, PE/Cy7, Rabbit
• Biozol Catalog Number: BSS-BS-18450R-PE-CY7
• Supplier Catalog Number: bs-18450R-PE-Cy7
• Alternative Catalog Number: BSS-BS-18450R-PE-CY7-100
• Manufacturer: Bioss
• Host: Rabbit
• Category: Antikörper
• Application: WB
• Species Reactivity: Mouse
• Conjugation: PE/Cy7
• Alternative Names: Oxysterols receptor LXR-beta, NR1H2, Liver X receptor beta, Nuclear receptor NER, Nuclear receptor subfamily 1 group H member 2, Ubiquitously-expressed nuclear receptor, NR1H2, LXRB, NER, UNR

Product Description

Nuclear receptor. Binds preferentially to double-stranded oligonucleotide direct repeats having the consensus half-site sequence 5-AGGTCA-3 and 4-nt spacing (DR-4). Regulates cholesterol uptake through MYLIP-dependent ubiquitination of LDLR, VLDLR and LRP8, DLDLR and LRP8. Interplays functionally with RORA for the regulation of genes involved in liver metabolism (By similarity). Exhibits a ligand-dependent transcriptional activation activity (PubMed:25661920).

Product Properties

• Clonality: Polyclonal
• Concentration: 1ug/ul
• NCBI: 7376
• UniProt: P55055
• Buffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
• Source: KLH conjugated synthetic peptide derived from human LXR beta
• Target: LXR beta

Application Notes

• Application Dilute: WB(1:300-5000)