phospho-MCSF Receptor (Tyr561) Polyclonal Antibody, Biotin Conjugated, Rabbit

Product Overview

• Article Name: phospho-MCSF Receptor (Tyr561) Polyclonal Antibody, Biotin Conjugated, Rabbit
• Biozol Catalog Number: BSS-BS-18735R-BIOTIN
• Supplier Catalog Number: bs-18735R-Biotin
• Alternative Catalog Number: BSS-BS-18735R-BIOTIN-100
• Manufacturer: Bioss
• Host: Rabbit
• Category: Antikörper
• Application: IHC-Fr, IHC-P
• Conjugation: Biotin
• Alternative Names: MCSF Receptor (phospho Y561), p-MCSF Receptor (phospho Y561), C FMS, CD 115, CD115, CD115 antigen, CFMS, Colony stimulating factor 1 receptor, Colony stimulating factor I receptor, CSF 1 R, CSF 1R, CSF-1 receptor, CSF-1-R, CSF1 R, CSF1R, CSF1R_HUMAN, CSFR, FIM 2, FIM2, FMS, FMS proto oncogene, FMS protooncogene, HDLS, M-CSF Receptor, M-CSF-R, Macrophage colony stimulating factor 1 receptor, Macrophage colony stimulating factor I receptor, Macrophage colony-stimulating factor 1 receptor, McDonough feline sarcoma viral (v fms) oncogene homolog, Oncogen FMS, Proto-oncogene c-Fms, V-FMS McDonough feline sarcoma viral oncogen homolog, formerly.

Product Description

This protein tyrosine kinase transmembrane receptor is the receptor for colony stimulating factor 1, a cytokine which controls the production, differentiation, and function of macrophages. This receptor mediates most if not all of the biological effects of this cytokine. Ligand binding activates the receptor kinase through a process of oligomerization and transphosphorylation. The encoded protein is a member of the CSF1/PDGF receptor family of tyrosine protein kinases and contains 5 immunoglobulin like C2 type domains. CD115 is expressed by cells of the monocytic lineage and by progenitor cells. Mutations in this gene have been associated with a predisposition to myeloid malignancy.

Product Properties

• Clonality: Polyclonal
• Concentration: 1ug/ul
• NCBI: 1436
• UniProt: P07333
• Buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
• Source: KLH conjugated synthetic peptide derived from human phospho-MCSF Receptor (Tyr561)
• Target: phospho-MCSF Receptor (Tyr561)

Application Notes

• Application Dilute: IHC-P(1:200-400), IHC-F(1:100-500)