RSPO3 Polyclonal Antibody, Biotin Conjugated, Rabbit

Product Overview

• Article Name: RSPO3 Polyclonal Antibody, Biotin Conjugated, Rabbit
• Biozol Catalog Number: BSS-BS-18877R-BIOTIN
• Supplier Catalog Number: bs-18877R-Biotin
• Alternative Catalog Number: BSS-BS-18877R-BIOTIN-100
• Manufacturer: Bioss
• Host: Rabbit
• Category: Antikörper
• Application: ELISA, WB
• Species Reactivity: Human
• Conjugation: Biotin
• Alternative Names: CRISTIN1, hPWTSR, hRspo3, Protein with TSP type-1 repeat, PWTSR, R-spondin 3 homolog, R-spondin-3 [Precursor], R-spondin-3, Roof plate specific spondin-3, Roof plate-specific spondin-3, RSPO3_HUMAN, Thrombospondin type I domain containing 2, Thrombospondin type-1 domain-containing protein 2, THSD2.

Product Description

Activator of the beta-catenin signaling cascade, leading to TCF-dependent gene activation. Acts both in the canonical Wnt/beta-catenin-dependent pathway, possibly via a direct interaction with Wnt proteins, and in a Wnt-independent beta catenin pathway through a receptor signaling pathway that may not use frizzled/LRP receptors. Acts as a ligand for frizzled FZD8 and LRP6. May negatively regulate the TGF-beta pathway.

Product Properties

• Clonality: Polyclonal
• Concentration: 1ug/ul
• NCBI: 84870
• UniProt: Q9BXY4
• Buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
• Source: KLH conjugated synthetic peptide derived from human RSPO3
• Target: RSPO3

Application Notes

• Application Dilute: WB(1:300-5000), ELISA(1:500-1000)