phospho-Smad2 (Ser250) Polyclonal Antibody, AbBy Fluor-405 Conjugated, BF405, Rabbit

Product Overview

• Article Name: phospho-Smad2 (Ser250) Polyclonal Antibody, AbBy Fluor-405 Conjugated, BF405, Rabbit
• Biozol Catalog Number: BSS-BS-20341R-BF405
• Supplier Catalog Number: bs-20341R-BF405
• Alternative Catalog Number: BSS-BS-20341R-BF405-100
• Manufacturer: Bioss
• Host: Rabbit
• Category: Antikörper
• Application: WB
• Species Reactivity: Human, Mouse, Rat
• Conjugation: BF405
• Alternative Names: Mothers against decapentaplegic homolog 2, SMAD2, MAD homolog 2, Mothers against DPP homolog 2, JV18-1, Mad-related protein 2, hMAD-2, SMAD family member 2, MADH2, MADR2

Product Description

Receptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases. Binds the TRE element in the promoter region of many genes that are regulated by TGF-beta and, on formation of the SMAD2/SMAD4 complex, activates transcription. May act as a tumor suppressor in colorectal carcinoma.

Product Properties

• Clonality: Polyclonal
• Concentration: 1ug/ul
• NCBI: 4087
• UniProt: Q15796
• Buffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
• Source: KLH conjugated synthetic peptide derived from human Anti-phospho-Smad2 (Ser250)
• Target: phospho-Smad2 (Ser250)

Application Notes

• Application Dilute: WB(1:300-5000)