phospho-Smad2 (Ser250) Polyclonal Antibody, PE Conjugated, Rabbit
Biozol Catalog Number:
BSS-BS-20341R-PE
Supplier Catalog Number:
bs-20341R-PE
Alternative Catalog Number:
BSS-BS-20341R-PE-100
Manufacturer:
Bioss
Host:
Rabbit
Category:
Antikörper
Application:
WB
Species Reactivity:
Human, Mouse, Rat
Conjugation:
PE
Alternative Names:
Mothers against decapentaplegic homolog 2, SMAD2, MAD homolog 2, Mothers against DPP homolog 2, JV18-1, Mad-related protein 2, hMAD-2, SMAD family member 2, MADH2, MADR2
Receptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases. Binds the TRE element in the promoter region of many genes that are regulated by TGF-beta and, on formation of the SMAD2/SMAD4 complex, activates transcription. May act as a tumor suppressor in colorectal carcinoma.