caspase-3 p17 subunit Polyclonal Antibody, RBITC Conjugated, Rabbit

Product Overview

• Article Name: caspase-3 p17 subunit Polyclonal Antibody, RBITC Conjugated, Rabbit
• Biozol Catalog Number: BSS-BS-20364R-RBITC
• Supplier Catalog Number: bs-20364R-RBITC
• Alternative Catalog Number: BSS-BS-20364R-RBITC-100
• Manufacturer: Bioss
• Host: Rabbit
• Category: Antikörper
• Application: FC, IF, WB
• Species Reactivity: Human, Mouse
• Conjugation: RBITC
• Alternative Names: Caspase-3 subunit p17, APOPAIN, CASP3, Caspase 3 apoptosis related cysteine protease, Caspase3, CPP32, CPP32B, Cysteine protease CPP32, Human cysteine protease CPP32 isoform alpha mRNA complete cds, PARP cleavage protease, SCA 1, SCA1, SREBP cleavage activity 1, Yama, CASP3_HUMAN, Caspase-3, CASP-3, Apopain, Protein Yama, SREBP cleavage activity 1, SCA-1.

Product Description

Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a 216-Asp-|-Gly-217 bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Involved in the cleavage of huntingtin. Triggers cell adhesion in sympathetic neurons through RET cleavage.

Product Properties

• Clonality: Polyclonal
• Concentration: 1ug/ul
• NCBI: 836
• UniProt: P42574
• Buffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
• Source: KLH conjugated synthetic peptide derived from human caspase-3 p17 subunit
• Target: caspase-3 p17 subunit

Application Notes

• Application Dilute: WB(1:300-5000), FCM(1:20-100), IF(IHC-P)(1:50-200), IF(IHC-F)(1:50-200), IF(ICC)(1:50-200)