IL-10 Polyclonal Antibody, PE Conjugated, Rabbit

Product Overview

• Article Name: IL-10 Polyclonal Antibody, PE Conjugated, Rabbit
• Biozol Catalog Number: BSS-BS-20373R-PE
• Supplier Catalog Number: bs-20373R-PE
• Alternative Catalog Number: BSS-BS-20373R-PE-100
• Manufacturer: Bioss
• Host: Rabbit
• Category: Antikörper
• Application: FC, WB
• Species Reactivity: Human, Mouse, Rat
• Conjugation: PE
• Alternative Names: CSIF, TGIF, GVHDS, IL-10, IL10A, Interleukin-10, Cytokine synthesis inhibitory factor, IL10

Product Description

Major immune regulatory cytokine that acts on many cells of the immune system where it has profound anti-inflammatory functions, limiting excessive tissue disruption caused by inflammation. Mechanistically, IL10 binds to its heterotetrameric receptor comprising IL10RA and IL10RB leading to JAK1 and STAT2-mediated phosphorylation of STAT3. IL-10 Inhibits the synthesis of a number of cytokines, including IFN-gamma, IL-2, IL-3, TNF and GM-CSF produced by activated macrophages and by helper T-cells.

Product Properties

• Clonality: Polyclonal
• Concentration: 1ug/ul
• NCBI: 3586
• UniProt: P22301
• Buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
• Source: KLH conjugated synthetic peptide derived from human IL-10
• Target: IL-10

Application Notes

• Application Dilute: WB(1:300-5000), FCM(1:20-100)