GLRB Polyclonal Antibody, RBITC Conjugated, Rabbit

Product Overview

• Article Name: GLRB Polyclonal Antibody, RBITC Conjugated, Rabbit
• Biozol Catalog Number: BSS-BS-20450R-RBITC
• Supplier Catalog Number: bs-20450R-RBITC
• Alternative Catalog Number: BSS-BS-20450R-RBITC-100
• Manufacturer: Bioss
• Host: Rabbit
• Category: Antikörper
• Application: IF, WB
• Species Reactivity: Mouse, Rat
• Conjugation: RBITC
• Alternative Names: Glycine receptor subunit beta, GLRB, Glycine receptor 58 kDa subunit

Product Description

Glycine receptors are ligand-gated chloride channels. GLRB does not form ligand-gated ion channels by itself, but is part of heteromeric ligand-gated chloride channels. Channel opening is triggered by extracellular glycine (PubMed:8717357, PubMed:15302677, PubMed:16144831, PubMed:22715885, PubMed:25445488, PubMed:11929858, PubMed:23238346). Heteropentameric channels composed of GLRB and GLRA1 are activated by lower glycine levels than homopentameric GLRA1 (PubMed:8717357). Plays an important role in the down-regulation of neuronal excitability (PubMed:11929858, PubMed:23238346). Contributes to the generation of inhibitory postsynaptic currents (PubMed:25445488).

Product Properties

• Clonality: Polyclonal
• Concentration: 1ug/ul
• NCBI: 2743
• UniProt: P48167
• Buffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
• Source: KLH conjugated synthetic peptide derived from human GLRB
• Target: GLRB

Application Notes

• Application Dilute: WB(1:300-5000), IF(IHC-P)(1:50-200), IF(IHC-F)(1:50-200), IF(ICC)(1:50-200)