Baculoviral IAP repeat containing 7, Baculoviral IAP repeat containing protein 7, BIRC 7, BIRC7, BIRC7_HUMAN, KIAP, Kidney inhibitor of apoptosis protein, LIVIN, Livin inhibitor of apotosis, Melanoma inhibitor of apoptosis protein, ML IAP, MLIAP, RING finger protein 50, RNF 50, RNF50, Inhibitors of apoptosis proterins Livin.,,
Livin is a novel member of the IAP protein family and contains a single baculoviral IAP repeat (BIR) domain and a RING finger domain and has two isoforms termed Livin alpha and Livin beta. The BIR domain is essential for inhibitory activity and interacts with caspases, while the RING finger domain sometimes enhances antiapoptotic activity but does not inhibit apoptosis alone. The two isoforms of Livin appear to have different functions and tissue distributions.
