CCN 2, CCN-2, CCN2, Connective Tissue Growth Factor, CTGF, Hcs 24, Hcs24, Hypertrophic chondrocyte specific protein 24, Hypertrophic chondrocyte-specific gene product 24, Insulin-like Growth Factor-Binding Protein 8, MGC102839, NOV 2, NOV2, Connective tissue growth factor, CCN family member 2, Hypertrophic chondrocyte-specific protein 24, Insulin-like growth-binding protein 8, IBP-8, IGF-binding protein 8, IGFBP8, IGFBP-8, connective tissue growth factor precursor, CTGF_HUMAN.
Major connective tissue mitoattractant secreted by vascular endothelial cells. Promotes proliferation and differentiation of chondrocytes. Mediates heparin- and divalent cation-dependent cell adhesion in many cell types including fibroblasts, myofibroblasts, endothelial and epithelial cells. Enhances fibroblast growth factor-induced DNA synthesis.
