IL-23R Polyclonal Antibody, Cy5 Conjugated, Rabbit

Catalog Number: BSS-BS-22608R-CY5
Article Name: IL-23R Polyclonal Antibody, Cy5 Conjugated, Rabbit
Biozol Catalog Number: BSS-BS-22608R-CY5
Supplier Catalog Number: bs-22608R-Cy5
Alternative Catalog Number: BSS-BS-22608R-CY5-100
Manufacturer: Bioss
Host: Rabbit
Category: Antikörper
Application: WB
Species Reactivity: Human
Conjugation: Cy5
Alternative Names: IL23 Receptor, IL-23R, IL23R, interleukin 23 receptor, IL 23R, IL-23 receptor, IL23R_HUMAN, Interleukin-23 receptor.
Associates with IL12RB1 to form the interleukin-23 receptor. Binds IL23 and mediates T-cells, NK cells and possibly certain macrophage/myeloid cells stimulation probably through activation of the Jak-Stat signaling cascade. IL23 functions in innate and adaptive immunity and may participate in acute response to infection in peripheral tissues. IL23 may be responsible for autoimmune inflammatory diseases and be important for tumorigenesis. Subunit : Heterodimer with IL12RB1. In presence of IL23, the heterodimer forms the IL23 receptor. Interacts with JAK2 and in presence of IL23 with STAT3.
Clonality: Polyclonal
Concentration: 1ug/ul
NCBI: 149233
UniProt: Q5VWK5
Buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Source: KLH conjugated synthetic peptide derived from human IL-23R
Purity: Purified by Protein A.
Target: IL-23R
Application Dilute: WB(1:300-5000)