CDKN1A/p21 Polyclonal Antibody, AbBy Fluor-680 Conjugated, BF680, Rabbit
Catalog Number:
BSS-BS-22795R-BF680
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| Article Name: | CDKN1A/p21 Polyclonal Antibody, AbBy Fluor-680 Conjugated, BF680, Rabbit |
| Biozol Catalog Number: | BSS-BS-22795R-BF680 |
| Supplier Catalog Number: | bs-22795R-BF680 |
| Alternative Catalog Number: | BSS-BS-22795R-BF680-100 |
| Manufacturer: | Bioss |
| Host: | Rabbit |
| Category: | Antikörper |
| Application: | IF |
| Species Reactivity: | Human, Mouse, Rat |
| Conjugation: | BF680 |
| Alternative Names: | p21, P21 protein, Activating Fragment 1, CAP20, Cation chloride cotransporter-interacting protein 1, CDK Interacting Protein 1, CDK-interacting protein 1, CDKI, CDKN 1, CDKN1, CDKN1A, CIP1, Cyclin Dependent Kinase Inhibitor 1A, Cyclin-dependent kinase inhibitor 1, Cyclin-dependent kinase inhibitor 1A (P21), Cyclin-dependent kinase inhibitor 1A (p21, Cip1), DNA Synthesis Inhibitor, MDA 6, MDA-6, MDA6, Melanoma Differentiation Associated Protein 6, Melanoma differentiation-associated protein 6, Melanoma differentiation-associated protein, p21CIP1, p21WAF, PIC1, SDI1, SLC12A9, WAF1, Wildtype p53 Activating Fragment 1, Wildtype p53-activated fragment 1, CDN1A_HUMAN. |
| May be the important intermediate by which p53/TP53 mediates its role as an inhibitor of cellular proliferation in response to DNA damage. Binds to and inhibits cyclin-dependent kinase activity, preventing phosphorylation of critical cyclin-dependent kinase substrates and blocking cell cycle progression. Functions in the nuclear localization and assembly of cyclin D-CDK4 complex and promotes its kinase activity towards RB1. At higher stoichiometric ratios, inhibits the kinase activity of the cyclin D-CDK4 complex. |
| Application Dilute: | IF(IF=1:100-500) |
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