CDKN1A/p21 Polyclonal Antibody, FITC Conjugated, Rabbit

Product Overview

• Article Name: CDKN1A/p21 Polyclonal Antibody, FITC Conjugated, Rabbit
• Biozol Catalog Number: BSS-BS-22795R-FITC
• Supplier Catalog Number: bs-22795R-FITC
• Alternative Catalog Number: BSS-BS-22795R-FITC-100
• Manufacturer: Bioss
• Host: Rabbit
• Category: Antikörper
• Application: IF
• Species Reactivity: Human, Mouse, Rat
• Conjugation: FITC
• Alternative Names: p21, P21 protein, Activating Fragment 1, CAP20, Cation chloride cotransporter-interacting protein 1, CDK Interacting Protein 1, CDK-interacting protein 1, CDKI, CDKN 1, CDKN1, CDKN1A, CIP1, Cyclin Dependent Kinase Inhibitor 1A, Cyclin-dependent kinase inhibitor 1, Cyclin-dependent kinase inhibitor 1A (P21), Cyclin-dependent kinase inhibitor 1A (p21, Cip1), DNA Synthesis Inhibitor, MDA 6, MDA-6, MDA6, Melanoma Differentiation Associated Protein 6, Melanoma differentiation-associated protein 6, Melanoma differentiation-associated protein, p21CIP1, p21WAF, PIC1, SDI1, SLC12A9, WAF1, Wildtype p53 Activating Fragment 1, Wildtype p53-activated fragment 1, CDN1A_HUMAN.

Product Description

May be the important intermediate by which p53/TP53 mediates its role as an inhibitor of cellular proliferation in response to DNA damage. Binds to and inhibits cyclin-dependent kinase activity, preventing phosphorylation of critical cyclin-dependent kinase substrates and blocking cell cycle progression. Functions in the nuclear localization and assembly of cyclin D-CDK4 complex and promotes its kinase activity towards RB1. At higher stoichiometric ratios, inhibits the kinase activity of the cyclin D-CDK4 complex.

Product Properties

• Clonality: Polyclonal
• Concentration: 1ug/ul
• NCBI: 12575
• UniProt: P39689
• Buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
• Source: KLH conjugated synthetic peptide derived from mouse CDKN1A/p21
• Target: CDKN1A/p21

Application Notes

• Application Dilute: IF(IF=1:100-500)