ZO1 tight junction protein, Tight junction protein 1, Tight junction protein ZO-1, Tight junction protein ZO1, TJP1, zo-1, Zo1, ZO1_HUMAN, Zona occludens 1, Zona occludens 1 protein, Zona occludens protein 1, Zonula occludens 1 protein, Zonula occludens protein 1.
The N-terminal may be involved in transducing a signal required for tight junction assembly, while the C-terminal may have specific properties of tight junctions. The alpha domain might be involved in stabilizing junctions. Plays a role in the regulation of cell migration by targeting CDC42BPB to the leading edge of migrating cells.