NQO1 Polyclonal Antibody, AbBy Fluor-488 Conjugated, BF488, Rabbit

Product Overview

• Article Name: NQO1 Polyclonal Antibody, AbBy Fluor-488 Conjugated, BF488, Rabbit
• Biozol Catalog Number: BSS-BS-23407R-BF488
• Supplier Catalog Number: bs-23407R-BF488
• Alternative Catalog Number: BSS-BS-23407R-BF488-100
• Manufacturer: Bioss
• Host: Rabbit
• Category: Antikörper
• Application: IF, WB
• Species Reactivity: Human, Mouse, Rat
• Conjugation: BF488
• Alternative Names: Azoreductase, Cytochrome b 5 reductase, DHQU, DIA 4, DIA4, Diaphorase (NADH/NADPH) (cytochrome b 5 reductase), Diaphorase (NADH/NADPH) (cytochrome b-5 reductase), Diaphorase (NADH/NADPH) (cytochrome b-5 reductase), Diaphorase (NADH/NADPH), Diaphorase 4, Dioxin inducible 1, DT diaphorase, DT-diaphorase, DTD, Menadione reductase, NAD(P)H dehydrogenase [quinone] 1, NAD(P)H dehydrogenase quinone 1, NAD(P)H menadione oxidoreductase 1 dioxin inducible, NAD(P)H: menadione oxidoreductase 1 dioxin inducible 1, NAD(P)H:menadione oxidoreductase 1, NAD(P)H:Quinone acceptor oxidoreductase type 1, NAD(P)H:quinone oxidoreductase 1, NAD(P)H:quinone oxireductase, NMOR 1, NMOR I, NMOR1, NMORI, NQO 1, NQO1, NQO1_HUMAN, Phylloquinone reductase, Phylloquinone reductase, QR 1, QR1, Quinone reductase 1, Quinone reductase 1.

Product Description

This gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. This FAD-binding protein forms homodimers and reduces quinones to hydroquinones. This proteins enzymatic activity prevents the one electron reduction of quinones that results in the production of radical species. Mutations in this gene have been associated with tardive dyskinesia (TD), an increased risk of hematotoxicity after exposure to benzene, and susceptibility to various forms of cancer. Altered expression of this protein has been seen in many tumors and is also associated with Alzheimers disease (AD). Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq].

Product Properties

• Clonality: Polyclonal
• Concentration: 1ug/ul
• NCBI: 18104
• UniProt: Q64669
• Buffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
• Source: KLH conjugated synthetic peptide derived from mouse NQO1
• Target: NQO1

Application Notes

• Application Dilute: WB(1:300-5000), IF(IHC-P)(1:50-200), IF(IHC-F)(1:50-200), IF(ICC)(1:50-200)