Patched Polyclonal Antibody, AbBy Fluor-488 Conjugated, BF488, Rabbit

Catalog Number: BSS-BS-24459R-BF488
Article Name: Patched Polyclonal Antibody, AbBy Fluor-488 Conjugated, BF488, Rabbit
Biozol Catalog Number: BSS-BS-24459R-BF488
Supplier Catalog Number: bs-24459R-BF488
Alternative Catalog Number: BSS-BS-24459R-BF488-100
Manufacturer: Bioss
Host: Rabbit
Category: Antikörper
Application: WB
Species Reactivity: Mouse, Rat
Conjugation: BF488
Alternative Names: Protein patched homolog 1, PTCH, PTC1, A230106A15Rik, BCNS, FLJ26746, FLJ42602, Holoprosencephaly 7, HPE7, mes, NBCCS, OTTHUMP00000021709, OTTHUMP00000021710, Patched, Patched (Drosophila) homolog, Patched 1, Patched homolog (Drosophila), Patched homolog 1 (Drosophila), Patched homolog 1, Patched protein homolog 1, PTC, PTC1, PTCH, PTCH protein +12b, PTCH protein +4, PTCH protein -10, PTCH protein, PTCH1, PTCH1 protein, PTCH11, Ptch2, , Patched / PTCH, PTC1_HUMAN.
Acts as a receptor for sonic hedgehog (SHH), indian hedgehog (IHH) and desert hedgehog (DHH). Associates with the smoothened protein (SMO) to transduce the hedgehogs proteins signal. Seems to have a tumor suppressor function, as inactivation of this protein is probably a necessary, if not sufficient step for tumorigenesis.
Clonality: Polyclonal
Concentration: 1ug/ul
NCBI: 5727
UniProt: Q13635
Buffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Source: KLH conjugated synthetic peptide derived from human Patched
Purity: Purified by Protein A.
Target: Patched
Application Dilute: WB(1:300-5000)