TNFR1 Polyclonal Antibody, PE-Cy5.5 Conjugated, PE/Cy5.5, Rabbit

Product Overview

• Article Name: TNFR1 Polyclonal Antibody, PE-Cy5.5 Conjugated, PE/Cy5.5, Rabbit
• Biozol Catalog Number: BSS-BS-2941R-PE-CY5.5
• Supplier Catalog Number: bs-2941R-PE-Cy5.5
• Alternative Catalog Number: BSS-BS-2941R-PE-CY5.5-100
• Manufacturer: Bioss
• Host: Rabbit
• Category: Antikörper
• Application: FC, WB
• Species Reactivity: Human, Mouse, Rat
• Conjugation: PE/Cy5.5
• Alternative Names: Tumor necrosis factor receptor superfamily member 1A, Tumor necrosis factor receptor 1, TNF-R1, Tumor necrosis factor receptor type I, TNF-RI, TNFR-I, p55, p60, CD120a, TNFRSF1A, TNFAR, TNFR1

Product Description

Receptor for TNFSF2/TNF-alpha and homotrimeric TNFSF1/lymphotoxin-alpha. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Contributes to the induction of non-cytocidal TNF effects including anti-viral state and activation of the acid sphingomyelinase.

Product Properties

• Clonality: Polyclonal
• Concentration: 1ug/ul
• NCBI: 7132
• UniProt: P19438
• Buffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
• Source: KLH conjugated synthetic peptide derived from human TNF Receptor I
• Target: TNFR1

Application Notes

• Application Dilute: WB(1:300-5000), FCM(1:20-100)