phospho-arfaptin 2 (Ser260) Polyclonal Antibody, Unconjugated, Rabbit

Product Overview

• Article Name: phospho-arfaptin 2 (Ser260) Polyclonal Antibody, Unconjugated, Rabbit
• Biozol Catalog Number: BSS-BS-3006R
• Supplier Catalog Number: bs-3006R
• Alternative Catalog Number: BSS-BS-3006R-100
• Manufacturer: Bioss
• Host: Rabbit
• Category: Antikörper
• Application: ELISA, IF, IHC-Fr, IHC-P, WB
• Species Reactivity: Human
• Conjugation: Unconjugated
• Alternative Names: ADP ribosylation factor interacting protein 2, Arfaptin 2, ARFIP2, Partner of RAC1, POR1, ARFP2_HUMAN.

Product Description

ARFIP2 is a ubiquitously expressed protein implicated in mediating cross talk between RAC and ARF small GTPases. It has been shown that ARFIP2 binds specifically to GTP-bound ARF1 and ARF6, but binds to Rac-GTP and Rac-GDP with similar affinities. The X-ray structure of arfaptin reveals an elongated, crescent-shaped dimer of 3-helix coiled-coils. Structures of arfaptin with Rac bound to either GDP or the slowly hydrolysable analog GMPPNP show that the switch regions adopt similar conformations in both complexes.

Product Properties

• Clonality: Polyclonal
• Concentration: 1ug/ul
• NCBI: 23647
• Buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
• Source: KLH conjugated synthetic phosphopeptide derived from human arfaptin 2 around the phosphorylation site of Ser260
• Target: phospho-arfaptin 2 (Ser260)

Application Notes

• Application Dilute: WB(1:300-5000), ELISA(1:500-1000), IHC-P(1:200-400), IHC-F(1:100-500), IF(IHC-P)(1:50-200), IF(IHC-F)(1:50-200), IF(ICC)(1:50-200)