Phospho-Bcr (Tyr177) Polyclonal Antibody, Unconjugated, Rabbit

Product Overview

• Article Name: Phospho-Bcr (Tyr177) Polyclonal Antibody, Unconjugated, Rabbit
• Biozol Catalog Number: BSS-BS-3067R
• Supplier Catalog Number: bs-3067R
• Alternative Catalog Number: BSS-BS-3067R-100
• Manufacturer: Bioss
• Host: Rabbit
• Category: Antikörper
• Application: ELISA, FC, IF, IHC-Fr, IHC-P, WB
• Conjugation: Unconjugated
• Alternative Names: Bcr phospho Y177, BcrTyr177, ALL, BCR 1, BCR/ABL FUSION GENE INCLUDED, BCR/FGFR1 FUSION GENE INCLUDED, BCR/PDGFRA FUSION GENE INCLUDED, BCR1, breakpoint cluster region, CML, PHL, BCR_HUMAN.

Product Description

The breakpoint cluster region protein (Bcr) is best know to be involved in genomic translocation with fusion partner Abl (Cbr-Abl) causing chronic myelogenous leukemia (CML). This 160 kDa protein contains a serine/threonine kinase domain, an SH2 binding domain, a GTP/GDP exchange domain and a C-term domain which functions as a GTPase activating protein for p21rac and CDC42. Additionally, Bcr is involved in signal transduction and can down regulate Ras mediated cell signaling.

Product Properties

• Clonality: Polyclonal
• Concentration: 1ug/ul
• NCBI: 613
• Buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
• Source: KLH conjugated synthetic phosphopeptide derived from human Bcr around the phosphorylation site of Tyr177 [PF(p-Y)VN]
• Target: Phospho-Bcr (Tyr177)

Application Notes

• Application Dilute: WB(1:300-5000), ELISA(1:500-1000), FCM(1:20-100), IHC-P(1:200-400), IHC-F(1:100-500), IF(IHC-P)(1:50-200), IF(IHC-F)(1:50-200), IF(ICC)(1:50-200)