Phospho-Bcr (Tyr177) Polyclonal Antibody, PE-Cy7 Conjugated, PE/Cy7, Rabbit

Product Overview

• Article Name: Phospho-Bcr (Tyr177) Polyclonal Antibody, PE-Cy7 Conjugated, PE/Cy7, Rabbit
• Biozol Catalog Number: BSS-BS-3067R-PE-CY7
• Supplier Catalog Number: bs-3067R-PE-Cy7
• Alternative Catalog Number: BSS-BS-3067R-PE-CY7-100
• Manufacturer: Bioss
• Host: Rabbit
• Category: Antikörper
• Application: FC, WB
• Conjugation: PE/Cy7
• Alternative Names: Bcr phospho Y177, BcrTyr177, ALL, BCR 1, BCR/ABL FUSION GENE INCLUDED, BCR/FGFR1 FUSION GENE INCLUDED, BCR/PDGFRA FUSION GENE INCLUDED, BCR1, breakpoint cluster region, CML, PHL, BCR_HUMAN.

Product Description

The breakpoint cluster region protein (Bcr) is best know to be involved in genomic translocation with fusion partner Abl (Cbr-Abl) causing chronic myelogenous leukemia (CML). This 160 kDa protein contains a serine/threonine kinase domain, an SH2 binding domain, a GTP/GDP exchange domain and a C-term domain which functions as a GTPase activating protein for p21rac and CDC42. Additionally, Bcr is involved in signal transduction and can down regulate Ras mediated cell signaling.

Product Properties

• Clonality: Polyclonal
• Concentration: 1ug/ul
• NCBI: 613
• Buffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
• Source: KLH conjugated synthetic phosphopeptide derived from human Bcr around the phosphorylation site of Tyr177 [PF(p-Y)VN]
• Target: Phospho-Bcr (Tyr177)

Application Notes

• Application Dilute: WB(1:300-5000), FCM(1:20-100)