Phospho-Cofilin (Ser3) Polyclonal Antibody, Unconjugated, Rabbit

Product Overview

• Article Name: Phospho-Cofilin (Ser3) Polyclonal Antibody, Unconjugated, Rabbit
• Biozol Catalog Number: BSS-BS-3099R
• Supplier Catalog Number: bs-3099R
• Alternative Catalog Number: BSS-BS-3099R-100
• Manufacturer: Bioss
• Host: Rabbit
• Category: Antikörper
• Application: IF, IHC-Fr, IHC-P, WB
• Species Reactivity: Mouse, Rat
• Conjugation: Unconjugated
• Alternative Names: CFL, cofilin, HEL-S-15, Cofilin-1, 18 kDa phosphoprotein, p18, Cofilin, non-muscle isoform, CFL1

Product Description

Binds to F-actin and exhibits pH-sensitive F-actin depolymerizing activity. Regulates actin cytoskeleton dynamics. Important for normal progress through mitosis and normal cytokinesis. Plays a role in the regulation of cell morphology and cytoskeletal organization. Required for the up-regulation of atypical chemokine receptor ACKR2 from endosomal compartment to cell membrane, increasing its efficiency in chemokine uptake and degradation.

Product Properties

• Clonality: Polyclonal
• Concentration: 1ug/ul
• NCBI: 1072
• Pubmed: 30594393
• UniProt: P23528
• Buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
• Source: KLH conjugated synthetic phosphopeptide derived from human Cofilin around the phosphorylation site of Ser3
• Target: Phospho-Cofilin (Ser3)

Application Notes

• Application Dilute: WB(1:300-5000), IHC-P(1:200-400), IHC-F(1:100-500), IF(IHC-P)(1:50-200), IF(IHC-F)(1:50-200), IF(ICC)(1:50-200)