phospho-CRK (Tyr221) Polyclonal Antibody, HRP Conjugated, Rabbit

Product Overview

• Article Name: phospho-CRK (Tyr221) Polyclonal Antibody, HRP Conjugated, Rabbit
• Biozol Catalog Number: BSS-BS-3121R-HRP
• Supplier Catalog Number: bs-3121R-HRP
• Alternative Catalog Number: BSS-BS-3121R-HRP-100
• Manufacturer: Bioss
• Host: Rabbit
• Category: Antikörper
• Application: ELISA, IHC-Fr, IHC-P, WB
• Species Reactivity: Other
• Conjugation: HRP
• Alternative Names: Adapter molecule crk, Proto-oncogene c-Crk, p38, CRK

Product Description

The Crk-I and Crk-II forms differ in their biological activities. Crk-II has less transforming activity than Crk-I. Crk-II mediates attachment-induced MAPK8 activation, membrane ruffling and cell motility in a Rac-dependent manner. Involved in phagocytosis of apoptotic cells and cell motility via its interaction with DOCK1 and DOCK4. May regulate the EFNA5-EPHA3 signaling.

Product Properties

• Clonality: Polyclonal
• Concentration: 1ug/ul
• NCBI: 1398
• Buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
• Source: KLH conjugated synthetic phosphopeptide derived from human Crk p38 around the phosphorylation site of Tyr221 [GP(p-Y)AQ]
• Target: phospho-CRK (Tyr221)

Application Notes

• Application Dilute: WB(1:300-5000), ELISA(1:500-1000), IHC-P(1:200-400), IHC-F(1:100-500)