phospho-Ephrin B (Ser300) Polyclonal Antibody, FITC Conjugated, Rabbit
Biozol Catalog Number:
BSS-BS-3128R-FITC
Supplier Catalog Number:
bs-3128R-FITC
Alternative Catalog Number:
BSS-BS-3128R-FITC-100
Manufacturer:
Bioss
Host:
Rabbit
Category:
Antikörper
Application:
IF, WB
Species Reactivity:
Human, Mouse, Rat
Conjugation:
FITC
Alternative Names:
Ephrin B phospho Y330, p-Ephrin B phospho Y330, CEK5 ligand, EFNB1, ELK L, EphrinB, Ephrin-B, ELK ligand, ELKL, EPH related receptor tyrosine kinase ligand 2, Ephrin B Precursor, Ephrin B1, Ephrin B2, LERK 2, LERK2, EFNB2_HUMAN.
Ephrin B proteins are thought to play key roles in cellular functions as diverse as neuronal migration and blood vessel development. Ephrin B molecules expressed at the membrane surface bind to the Ephrin B family receptors on target cells during cell to cell contact. This interaction leads to cell signaling in the target cell but also generates a reverse signal in the cell expressing Ephrin B on its surface. This reverse signaling event is thought to be critical for vessel maturation and neuronal development. Importantly, tyrosine phosphorylation of Ephrin B is thought to be a critical component of this reverse signaling event. Recent work demonstrated that Tyr331 of Ephrin B was phosphorylated in HEK293 cells after stimulation by the soluble Ephrin B2 receptor tyrosine kinase.
