Phospho-NMDAR2B (Tyr1070) Polyclonal Antibody, Cy7 Conjugated, Rabbit

Product Overview

• Article Name: Phospho-NMDAR2B (Tyr1070) Polyclonal Antibody, Cy7 Conjugated, Rabbit
• Biozol Catalog Number: BSS-BS-3306R-CY7
• Supplier Catalog Number: bs-3306R-Cy7
• Alternative Catalog Number: BSS-BS-3306R-CY7-100
• Manufacturer: Bioss
• Host: Rabbit
• Category: Antikörper
• Application: IF, WB
• Conjugation: Cy7
• Alternative Names: MRD6, NR2B, hNR3, GluN2B, NMDAR2B, Glutamate receptor ionotropic, NMDA 2B, Glutamate [NMDA] receptor subunit epsilon-2, N-methyl D-aspartate receptor subtype 2B, N-methyl-D-aspartate receptor subunit 3, NR3, GRIN2B

Product Description

NMDA receptor subtype of glutamate-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Mediated by glycine. In concert with DAPK1 at extrasynaptic sites, acts as a central mediator for stroke damage. Its phosphorylation at Ser-1303 by DAPK1 enhances synaptic NMDA receptor channel activity inducing injurious Ca2+ influx through them, resulting in an irreversible neuronal death (By similarity).

Product Properties

• Clonality: Polyclonal
• Concentration: 1ug/ul
• NCBI: 2904
• UniProt: Q13224
• Buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
• Source: KLH conjugated synthetic phosphopeptide derived from human NMDAR2B around the phosphorylation site of Tyr1070
• Target: Phospho-NMDAR2B (Tyr1070)

Application Notes

• Application Dilute: WB(1:300-5000), IF(IHC-P)(1:50-200), IF(IHC-F)(1:50-200), IF(ICC)(1:50-200)