phospho-PI3 kinase p85 alpha + gamma (Tyr467 + Tyr199) Polyclonal Antibody, PE-Cy5 Conjugated, PE/Cy5, Rabbit

Product Overview

• Article Name: phospho-PI3 kinase p85 alpha + gamma (Tyr467 + Tyr199) Polyclonal Antibody, PE-Cy5 Conjugated, PE/Cy5, Rabbit
• Biozol Catalog Number: BSS-BS-3332R-PE-CY5
• Supplier Catalog Number: bs-3332R-PE-Cy5
• Alternative Catalog Number: BSS-BS-3332R-PE-CY5-100
• Manufacturer: Bioss
• Host: Rabbit
• Category: Antikörper
• Application: FC, WB
• Species Reactivity: Human, Rat
• Conjugation: PE/Cy5
• Alternative Names: p85, AGM7, GRB1, IMD36, p85-ALPHA, Phosphatidylinositol 3-kinase regulatory subunit alpha, PI3-kinase regulatory subunit alpha, PI3K regulatory subunit alpha, PtdIns-3-kinase regulatory subunit alpha, Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha, PI3-kinase subunit p85-alpha, PtdIns-3-kinase regulatory subunit p85-alpha, PIK3R1

Product Description

Binds to activated (phosphorylated) protein-Tyr kinases, through its SH2 domain, and acts as an adapter, mediating the association of the p11 catalytic unit to the plasma membrane. Necessary for the insulin-stimulated increase in glucose uptake and glycogen synthesis in insulin-sensitive tissues. Plays an important role in signaling in response to FGFR1, FGFR2, FGFR3, FGFR4, KITLG/SCF, KIT, PDGFRA and PDGFRB. Likewise, plays a role in ITGB2 signaling.

Product Properties

• Clonality: Polyclonal
• Concentration: 1ug/ul
• NCBI: 5295
• UniProt: P27986
• Buffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
• Source: KLH conjugated synthetic phosphopeptide derived from human PI3K around the phosphorylation site of p85 alphaTyr467
• Target: phospho-PI3 kinase p85 alpha + gamma (Tyr467 + Tyr199)

Application Notes

• Application Dilute: WB(1:300-5000), FCM(1:20-100)