5DII, D2, Deiodinase, iodothyronine, type II, DIOII, ITDI2, SelY, Thyroxine deiodinase, type II, TXDI2, Type 2 DI, Type II 5 deiodinase, Type II iodothyronine deiodinase.
DIO2 belongs to the iodothyronine deiodinase family and is responsible for the deiodination of T4 (3,5,3,5-tetraiodothyronine) into T3 (3,5,3-triiodothyronine). It is essential for providing the brain with appropriate levels of T3 during the critical per