AMPK beta 2 Polyclonal Antibody, PE Conjugated, Rabbit
Biozol Catalog Number:
BSS-BS-3967R-PE
Supplier Catalog Number:
bs-3967R-PE
Alternative Catalog Number:
BSS-BS-3967R-PE-100
Manufacturer:
Bioss
Host:
Rabbit
Category:
Antikörper
Application:
IF
Species Reactivity:
Human
Conjugation:
PE
Alternative Names:
AMP activated protein kinase beta 2 non catalytic subunit, AMPK beta 2, AMPK beta 2 chain, PRKAB 2, Protein kinase AMP activated beta 2 non catalytic subunit, PRKAB1, AMPK subunit beta-1, AMPKb
PRKAB2 ans PRKAB1 are regulatory subunits of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status and plays a role in protecting cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. AMPK is responsible for the regulation of fatty acid synthesis by phosphorylation of acetyl-CoA carboxylase (ACC). It also regulates cholesterol synthesis via phosphorylation and inactivation of hydroxymethylglutaryl-CoA reductase (HMGCR) and hormone-sensitive lipase. PRKAB2 may be a positive regulator of AMPK activity.
