Recombinant human Lck protein isoform 3 , N-His, Unconjugated

Product Overview

• Article Name: Recombinant human Lck protein isoform 3 , N-His, Unconjugated
• Biozol Catalog Number: BSS-BS-41321P
• Supplier Catalog Number: bs-41321P
• Alternative Catalog Number: BSS-BS-41321P-100,BSS-BS-41321P-500
• Manufacturer: Bioss
• Category: Proteine/Peptide
• Species Reactivity: Other
• Conjugation: Unconjugated

Product Description

This gene is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein is a key signaling molecule in the selection and maturation of developing T-cells. It contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to the plasma membrane and pericentrosomal vesicles, and binds to cell surface receptors, including CD4 and CD8, and other signaling molecules. Multiple alternatively spliced variants, encoding the same protein, have been described. [provided by RefSeq, Jul 2008].

Product Properties

• Tag: N-His
• NCBI: 3932
• UniProt: P06239
• Buffer: 4M urea (pH9.0) with 20mM Tris-HCl.
• Source: Recombinant human Lck protein isoform 3 is expressed in E.coli with N-His. It contains the amino acid sequence of 222-539/539
• Expression System: E.coli
• Purity: > 90% as determined by SDS- PAGE