Recombinant human CH25H protein, N-His, Unconjugated
Biozol Catalog Number:
BSS-BS-41322P
Supplier Catalog Number:
bs-41322P
Alternative Catalog Number:
BSS-BS-41322P-100,BSS-BS-41322P-500
Manufacturer:
Bioss
Category:
Proteine/Peptide
Application:
ELISA
Species Reactivity:
Other
Conjugation:
Unconjugated
CH25H (Cholesterol 25-hydroxylase), also known as h25OH, is a 272 amino acid endoplasmic membrane protein that belongs to the sterol desaturase family. CH25H contains clusters of histidine residues essential for catalytic activity and is involved in cholesterol and lipid metabolism. CH25H catalyzes the formation of 25-hydroxycholesterol from cholesterol leading to the repression of cholesterol biosynthetic enzymes. CH25H regulates lipid metabolism by synthesizing a corepressor that blocks sterol regulatory element binding protein (SREBP) processing. CH25H utilizes diiron cofactors to catalyze the hydroxylation of hydrophobic substrates.
