Recombinant human RAMP1 protein, N-GST & C-His, Unconjugated

Product Overview

• Article Name: Recombinant human RAMP1 protein, N-GST & C-His, Unconjugated
• Biozol Catalog Number: BSS-BS-41350P
• Supplier Catalog Number: bs-41350P
• Alternative Catalog Number: BSS-BS-41350P-100,BSS-BS-41350P-500
• Manufacturer: Bioss
• Category: Proteine/Peptide
• Application: ELISA
• Species Reactivity: Other
• Conjugation: Unconjugated

Product Description

The protein encoded by this gene is a member of the RAMP family of single transmembrane domain proteins, called receptor (calcitonin) activity modifying proteins (RAMPs). RAMPs are type I transmembrane proteins with an extracellular N terminus and a cytoplasmic C terminus. RAMPs are required to transport calcitonin receptor like receptor (CRLR) to the plasma membrane. CRLR, a receptor with seven transmembrane domains, can function as either a calcitonin gene related peptide (CGRP) receptor or an adrenomedullin receptor, depending on which members of the RAMP family are expressed. In the presence of this (RAMP1) protein, CRLR functions as a CGRP receptor. The RAMP1 protein is involved in the terminal glycosylation, maturation, and presentation of the CGRP receptor to the cell surface.

Product Properties

• Tag: N-GST&C-His
• UniProt: O60894
• Buffer: 4M Urea (pH9.0).
• Source: Recombinant human RAMP1 protein, N-GST & C-His protein is expressed in E.coli with N-GST&C-His. It contains the amino acid sequence of 27-117/148.
• Expression System: E.coli
• Purity: > 90% as determined by SDS- PAGE