Recombinant human PALB2 protein, Unconjugated

Product Overview

• Article Name: Recombinant human PALB2 protein, Unconjugated
• Biozol Catalog Number: BSS-BS-42066P
• Supplier Catalog Number: bs-42066P
• Alternative Catalog Number: BSS-BS-42066P-20,BSS-BS-42066P-100,BSS-BS-42066P-500
• Manufacturer: Bioss
• Category: Proteine/Peptide
• Species Reactivity: Other
• Conjugation: Unconjugated

Product Description

This gene encodes a protein that may function in tumor suppression. This protein binds to and colocalizes with the breast cancer 2 early onset protein (BRCA2) in nuclear foci and likely permits the stable intranuclear localization and accumulation of BRCA2. Essential partner of BRCA2 that promotes the localization and stability of BRCA2. Also enables its recombinational repair and checkpoint functions of BRCA2. May act by promoting stable association of BRCA2 with nuclear structures, allowing BRCA2 to escape the effects of proteosome-mediated degradation.

Product Properties

• Tag: His&Trx&S
• NCBI: 79728
• UniProt: Q86YC2
• Buffer: 0.01M TBS(pH7.4)
• Source: Recombinant human PALB2 protein is expressed in E.coli with His&Trx&S. It contains the amino acid sequence of 841-1186/1186
• Expression System: E.coli
• Purity: > 90% as determined by SDS- PAGE