Recombinant human PALB2 protein, APC Conjugated

Catalog Number: BSS-BS-42066P-APC
Article Name: Recombinant human PALB2 protein, APC Conjugated
Biozol Catalog Number: BSS-BS-42066P-APC
Supplier Catalog Number: bs-42066P-APC
Alternative Catalog Number: BSS-BS-42066P-APC-20,BSS-BS-42066P-APC-100,BSS-BS-42066P-APC-500
Manufacturer: Bioss
Category: Proteine/Peptide
Species Reactivity: Other
Conjugation: APC
This gene encodes a protein that may function in tumor suppression. This protein binds to and colocalizes with the breast cancer 2 early onset protein (BRCA2) in nuclear foci and likely permits the stable intranuclear localization and accumulation of BRCA2. Essential partner of BRCA2 that promotes the localization and stability of BRCA2. Also enables its recombinational repair and checkpoint functions of BRCA2. May act by promoting stable association of BRCA2 with nuclear structures, allowing BRCA2 to escape the effects of proteosome-mediated degradation.
Tag: His&Trx&S
NCBI: 79728
UniProt: Q86YC2
Buffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Source: Recombinant human PALB2 protein is expressed in E.coli with His&Trx&S. It contains the amino acid sequence of 841-1186/1186
Expression System: E.coli
Purity: > 90% as determined by SDS- PAGE