Recombinant human CD86 protein, C-His, Unconjugated

Product Overview

• Article Name: Recombinant human CD86 protein, C-His, Unconjugated
• Biozol Catalog Number: BSS-BS-42111P
• Supplier Catalog Number: bs-42111P
• Alternative Catalog Number: BSS-BS-42111P-20,BSS-BS-42111P-100,BSS-BS-42111P-500
• Manufacturer: Bioss
• Category: Proteine/Peptide
• Species Reactivity: Other
• Conjugation: Unconjugated

Product Description

This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms.[provided by RefSeq, May 2011].

Product Properties

• Tag: C-His
• NCBI: 942
• UniProt: P42081
• Buffer: 0.01M TBS(pH7.4)
• Source: Recombinant human CD86 protein is expressed in E.coli with C-His. It contains the amino acid sequence of 27-247/329
• Expression System: HEK293
• Purity: > 90% as determined by SDS- PAGE