Recombinant human GBP2 protein, N-His, Unconjugated

Product Overview

• Article Name: Recombinant human GBP2 protein, N-His, Unconjugated
• Biozol Catalog Number: BSS-BS-42139P
• Supplier Catalog Number: bs-42139P
• Alternative Catalog Number: BSS-BS-42139P-100,BSS-BS-42139P-500
• Manufacturer: Bioss
• Category: Proteine/Peptide
• Species Reactivity: Other
• Conjugation: Unconjugated

Product Description

Guanylate-binding proteins, GBP1 and GBP2 are GTP-binding proteins with a high-turnover GTPase activity and an antiviral effect (1-4). GBP1 mediates an antiviral effect against vesicular stomatitis virus and encephalomyocarditis virus and plays a role in the IFN-mediated antiviral response against these viruses (4). GBP1 and GBP2 belong to a group of large GTP-binding proteins with a high concentration-dependent GTPase activity that have the common ability to undergo oligomerization (1). GBP1 and GBP2 are bone marrow-derived GTPases encoded by interferon-activated genes and are inducible following IFN treatment (2,3). Specifically, GBP1 is expressed in cultured mammary epithelial tumor cell lines after treatment with IFN-gamma and LPS (5).

Product Properties

• Tag: N-His
• NCBI: 2634
• UniProt: P32456
• Buffer: 20mM Tris (pH8.0) with 8M Urea.
• Source: Recombinant human GBP2 protein is expressed in E.coli with N-His. It contains the amino acid sequence of 50-306/591
• Expression System: E.coli
• Purity: > 90% as determined by SDS- PAGE