Recombinant human DUOX1 protein, N-His, Unconjugated

Product Overview

• Article Name: Recombinant human DUOX1 protein, N-His, Unconjugated
• Biozol Catalog Number: BSS-BS-42186P
• Supplier Catalog Number: bs-42186P
• Alternative Catalog Number: BSS-BS-42186P-100,BSS-BS-42186P-500
• Manufacturer: Bioss
• Category: Proteine/Peptide
• Species Reactivity: Other
• Conjugation: Unconjugated

Product Description

Dual oxidase 1 (DUOX1), a homolog of glycoprotein p91Phox, is expressed in airway epithelium and generates reactive oxygen species (ROS). DUOX1 is a multi-pass membrane protein predominantly expressed in thyrocytes and tracheal surface epithelial cells, as well as thyroid, trachea and bronchium. DUOX1 generates hydrogen peroxide, which is crucial for thyroid peroxidase and lactoperoxidase. It is also involved in thyroid hormone synthesis and lactoperoxidase-mediated antimicrobial defense in mucosa. DUOX1, which also plays a role in mucin expression, is widely expressed in fetal tissues.

Product Properties

• Tag: N-His
• NCBI: 53905
• UniProt: Q9NRD9
• Buffer: 20mM Tris-HCl (pH8.0) with 8M Urea and 5mM DTT.
• Source: Recombinant human DUOX1 protein is expressed in E.coli with N-His. It contains the amino acid sequence of 1270-1551/1551
• Expression System: E.coli
• Purity: > 90% as determined by SDS- PAGE