Recombinant human LPL protein, N-His, Unconjugated

Catalog Number: BSS-BS-42218P
Article Name: Recombinant human LPL protein, N-His, Unconjugated
Biozol Catalog Number: BSS-BS-42218P
Supplier Catalog Number: bs-42218P
Alternative Catalog Number: BSS-BS-42218P-100,BSS-BS-42218P-500
Manufacturer: Bioss
Category: Proteine/Peptide
Species Reactivity: Other
Conjugation: Unconjugated
Lipoprotein lipase (LPL) is the central enzyme in plasma triglyceride hydrolysis and is secreted by macrophages in the subendothelial space. Evidence has been provided that LPL produced by macrophages in the vessel wall exerts proatherogenic effects. The atherogenic effects of LPL have been mainly attributed to its ability to favor lipid accumulation within macrophages present in the atherosclerotic lesion. Recently, it has also been shown that LPL promote the development of atherosclerosis through facilitation of monocyte adhesion to endothelial cells, stimulation of tumor necrosis factor alpha (TNF ) secretion and induction of vascular smooth muscle cell proliferation.
Tag: N-His
NCBI: 4023
UniProt: P06858
Buffer: 20mM Tris-HCl (pH8.0) with 8M Urea.
Source: Recombinant human LPL protein is expressed in E.coli with N-His. It contains the amino acid sequence of 172-385/475
Expression System: E.coli
Purity: > 90% as determined by SDS- PAGE