Recombinant human CD11a protein, N-His, Unconjugated
Biozol Catalog Number:
BSS-BS-42274P
Supplier Catalog Number:
bs-42274P
Alternative Catalog Number:
BSS-BS-42274P-100,BSS-BS-42274P-500
Manufacturer:
Bioss
Category:
Proteine/Peptide
Species Reactivity:
Other
Conjugation:
Unconjugated
ITGAL encodes the integrin alpha L chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form the integrin lymphocyte function-associated antigen-1 (LFA-1), which is expressed on all leukocytes. LFA-1 plays a central role in leukocyte intercellular adhesion through interactions with its ligands, ICAMs 1-3 (intercellular adhesion molecules 1 through 3), and also functions in lymphocyte costimulatory signaling. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]