Recombinant human PPARGC1A, N-Trx-His, Unconjugated

Product Overview

• Article Name: Recombinant human PPARGC1A, N-Trx-His, Unconjugated
• Biozol Catalog Number: BSS-BS-42280P
• Supplier Catalog Number: bs-42280P
• Alternative Catalog Number: BSS-BS-42280P-20,BSS-BS-42280P-100,BSS-BS-42280P-500
• Manufacturer: Bioss
• Category: Proteine/Peptide
• Species Reactivity: Other
• Conjugation: Unconjugated

Product Description

The protein encoded by this gene is a transcriptional coactivator that regulates the genes involved in energy metabolism. This protein interacts with PPARgamma, which permits the interaction of this protein with multiple transcription factors. This protein can interact with, and regulate the activities of cAMP response element binding protein (CREB) and nuclear respiratory factors (NRFs). It provides a direct link between external physiological stimuli and the regulation of mitochondrial biogenesis, and is a major factor that regulates muscle fiber type determination. This protein may be also involved in controlling blood pressure, regulating cellular cholesterol homoeostasis, and the development of obesity (referenced from entrez gene.

Product Properties

• Tag: N-Trx-His
• NCBI: 10891
• UniProt: Q9UBK2
• Buffer: 0.01M TBS(pH7.4)
• Source: Recombinant human PPARGC1A is expressed in E.coli with N-Trx-His. It contains the amino acid sequence of 11-280/798
• Expression System: E.coli
• Purity: > 90% as determined by SDS- PAGE